Fragment 176-191 & CJC-1295 & Ipamorelin Blend (12mg)

Name: Fragment 176-191 & CJC-1295 & Ipamorelin Blend (12mg) - Planex Supplies
SKU: Fragment 176-191 & CJC-1295 & Ipamorelin Blend (12mg)
Price: 87.00 USD
Availability: InStock

$87.00

Buy the high-purity Fragment 176-191, CJC-1295 & Ipamorelin Peptide Blend (12mg) from Planex Supplies. This advanced 3-in-1 research formulation combines a highly selective lipolytic growth hormone fragment with dual-action growth hormone secretagogues (GHS) to study accelerated fat mobilization, somatotroph cell signaling, and skeletal tissue remodeling. Every batch is independently USA-tested with transparent, documented Certificates of Analysis (COAs) to guarantee standard-setting laboratory integrity.

SKU: Fragment 176-191 & CJC-1295 & Ipamorelin Blend (12mg) Category: Peptide Blends Tags: 12mg Blend, Bone Density, Buy Peptides Online, CJC-1295, Fragment 176-191, Ipamorelin, Lab Supplies, Lipolysis, Neuroendocrine, Peptide Blend, Planex Supplies, Research Peptides, Secretagogue, Thermogenesis, USA Tested

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Advanced Triple-Action Metabolic & Neuroendocrine Research Blend

The Fragment 176-191 & CJC-1295 & Ipamorelin Blend (12mg) from Planex Supplies presents a highly sophisticated multi-peptide matrix designed for advanced preclinical experimentation. By combining the primary lipolytic segment of human growth hormone (hGH) with two non-competing growth hormone secretagogues (GHRH and ghrelin receptor mimetics), this composite 12mg formulation allows investigators to study immediate versus sustained endocrine pulsatility alongside specific lipid-mobilizing pathways in mammalian models.

Comprehensive Technical Specifications:

Fragment 176-191 (Lipolytic Fragment)

Molecular Formula: C₇₈H₁₂₅N₂₃O₂₃S₂
Molecular Weight: 1817.1 g/mol
Sequence: Tyr-Leu-Arg-Ile-Val-Gin-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe

CJC-1295 (Modified GRF 1-29) (Note: Formulated without DAC for precise natural pulsatile simulation)

Molecular Formula: C₁₅₂H₂₅₂N₄₄O₄₂
Molecular Weight: 3367.954 g/mol
Sequence: H-Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-Lys(Mal)-NH2

Ipamorelin

Molecular Formula: C₃₈H₄₉N₉O₅
Molecular Weight: 711.86 g/mol
Sequence: Aib-His-D-2Nal-D-Phe-Lys-NH2

Key Areas of Scientific Research & Mechanisms:

Targeted Lipolysis & Beta-3 Adrenergic Signaling: Fragment 176-191 isolates the specific region of the hGH molecule responsible for fat restriction and breakdown. Research suggests it selectively targets beta-3 adrenergic receptors (ADRB3) to amplify lipolysis and suppress lipogenesis within adipose tissue cells while driving thermogenesis models in skeletal muscle. Crucially, literature observes that it isolates these traits without inducing unwanted hGH traits like long-bone growth, edema, or altered insulin sensitivity.
Somatotroph Cell Proliferation: CJC-1295 behaves as a stabilized GHRH analogue that stimulates pituitary somatotroph cells. Preclinical data using GHRH gene deletion (GHRHKO) murine models indicates that frequent introduction preserves standard weight, skeletal dimensions, and lean mass profile without increasing adiposity. Immunohistochemistry reveals that CJC-1295 drives a clear rise in total pituitary RNA and GH mRNA, indicating targeted cellular proliferation.
Biphasic Neuroendocrine Kinetics: Investigators study this specific combination to evaluate a balanced, biphasic pharmacokinetic model. Ipamorelin, a selective ghrelin mimetic with a brief 2-hour half-life, triggers an immediate, rapid short-term pulse of growth hormone via calcium channel and adrenergic pathways. Conversely, CJC-1295 delivers extended, long-term influence to sustain baseline concentrations and maximize overall physiological availability without receptor desensitization.
Extracellular Matrix & Skeletal Mineralization: Beyond metabolic pathways, both Ipamorelin and Fragment 176-191 are heavily evaluated for structural repair modeling. Real-time DXA and peripheral quantitative computed tomography (pQCT) scans indicate that Ipamorelin acts directly on osteoblasts to enhance total bone cross-sectional area, tibial dimensions, and vertebral bone mineral content (BMC), making this blend a versatile choice for studying cell-aging mitigation.

The Planex Supplies Quality Standard

At Planex Supplies, we execute rigid quality control protocols to protect the integrity and precision of your laboratory data. Our 12mg Fragment + CJC-1295 + Ipamorelin blend is synthesized to high technical tolerances and verified via high-performance liquid chromatography (HPLC). Every single batch is backed by a fully transparent, documented Certificate of Analysis (COA) issued by an independent laboratory in the United States.

Verified Purity: ≥ 99% purity guaranteed through mass spectrometry and HPLC profiling.
USA Vetted: Independent laboratory testing ensures absolute structural identity, correct molecular mass, and zero cross-contaminants.
Research Use Only: This compound is synthesized exclusively for in vitro laboratory experimentation and preclinical evaluation.