CJC-1295 & Ipamorelin Peptide Blend

Name: CJC-1295 & Ipamorelin Peptide Blend - Planex Supplies
SKU: CJC-1295 & Ipamorelin Peptide Blend
Price: 81.00 USD
Availability: InStock

$81.00

Buy the premium CJC-1295 & Ipamorelin Peptide Blend from Planex Supplies. This advanced dual-action research formulation leverages two distinct pathways to examine growth hormone axis kinetics, somatotroph cell proliferation, and gastric motility. Every batch is independently USA-tested with transparent, documented Certificates of Analysis (COAs) to guarantee standard-setting laboratory results.

SKU: CJC-1295 & Ipamorelin Peptide Blend Category: Peptide Blends Tags: Buy Peptides Online, CJC-1295, Gastric Motility, GHRH Analog, Ipamorelin, Lab Supplies, Peptide Blend, Pituitary Research, Planex Supplies, Research Peptides, Secretagogue, Somatotroph, USA Tested

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Advanced Dual-Action Peptide Secretagogue Research

The CJC-1295 & Ipamorelin Peptide Blend from Planex Supplies is a highly selective combination designed to study the growth hormone axis through two completely independent pathways. By pairing CJC-1295, a synthetic GHRH analog, with Ipamorelin, a highly selective ghrelin mimetic, this composite formulation avoids receptor competition while offering a stable system for evaluating dual-pathway neuroendocrine signaling in preclinical laboratory models.

Comprehensive Technical Specifications:

CJC-1295 (Modified GRF 1-29) (Note: Engineered without DAC for natural pulsatile simulation)

Molecular Formula: C₁₅₂H₂₅₂N₄₄O₄₂
Molecular Weight: 3367.954 g/mol
Sequence: H-Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-Lys(Mal)-NH2

Ipamorelin

Molecular Formula: C₃₈H₄₉N₉O₅
Molecular Weight: 711.86 g/mol
Sequence: Aib-His-D-2-Nal-D-Phe-Lys-NH2

Key Areas of Scientific Research & Mechanisms:

Pituitary G-Protein Signal Transduction: CJC-1295 targets GHRH receptors on somatotroph cells in the anterior pituitary. Upon binding, conformational shifts activate intracellular G-proteins, stimulating second messengers like cAMP and IP3. This cascade activates protein kinases to phosphorylate specific transcription factors within the nucleus, upregulating the transcription of genes associated with growth hormone synthesis. This mechanism ultimately triggers secretory vesicle fusion, prompting high-amplitude, pulsatile GH release.
Somatotroph Proliferation & Body Composition: In GHRH gene ablation (GHRHKO) murine research models, regular introduction of CJC-1295 has been observed to normalize skeletal dimensions, lean mass distribution, and overall weight growth profiles. Immunohistochemistry analysis indicates that CJC-1295 triggers a distinct increase in total pituitary RNA and GH mRNA levels, pointing to a localized proliferation of endogenous GH-producing somatotroph cells.
Receptor Selectivity & Growth Baseline: Ipamorelin functions as a highly specific agonist of the growth hormone/ghrelin secretagogue receptor (GHS-R1a). It behaves as a molecular mimic of natural ghrelin to drive baseline expression levels of GH. A key area of study is its unique selectivity profile; unlike early-generation compounds, Ipamorelin shows zero impact on auxiliary pituitary hormones, leaving cortisol, prolactin, follicle-stimulating hormone (FSH), luteinizing hormone (LH), and ACTH levels completely unaffected.
Gastric Emptying & Smooth Muscle Motility: Beyond endocrine pathways, Ipamorelin’s ghrelin receptor affinity makes it a premier model for digestive system research. Preclinical postoperative models suggest Ipamorelin reverses the sharp smooth muscle contractile inhibition caused by surgical intervention. By restoring acetylcholine and electrical field stimulation responses, it significantly accelerates delayed gastric emptying and supports energy balance modeling via serum leptin regulation.

The Planex Supplies Quality Standard

At Planex Supplies, we implement stringent quality control metrics to ensure the structural integrity and precision of your laboratory chemicals. Our CJC-1295 + Ipamorelin blend is synthesized to precise tolerances and verified through high-performance liquid chromatography (HPLC). We back every batch with fully documented, third-party Certificates of Analysis (COAs) analyzed entirely in the United States.

Verified Purity: ≥ 99% purity guaranteed through mass spectrometry and HPLC profiling.
USA Vetted: Every batch is independently verified to ensure accurate compound stability and structural concentration.
Research Use Only: This compound is synthesized exclusively for in vitro laboratory experimentation and preclinical evaluation.