Buy Tesamorelin & CJC-1295 (Mod GRF 1-29) & Ipamorelin Blend (12mg)

Name: Buy Tesamorelin & CJC-1295 (Mod GRF 1-29) & Ipamorelin Blend (12mg) - Planex Supplies
SKU: Tesamorelin & CJC-1295
Price: 109.00 USD
Availability: InStock

$109.00

Buy the premium Tesamorelin, CJC-1295 & Ipamorelin Peptide Blend from Planex Supplies. This advanced 3-in-1 research matrix integrates a lipodystrophy-studied full-length GHRH analog with a highly stable short-chain GHRH mimetic and a highly selective growth hormone secretagogue (GHS). Engineered for deep preclinical evaluation, this formula is optimized to study somatotroph cell kinetics, secondary messenger cascades, and downstream growth factor profiles. Every batch is independently USA-tested with transparent, documented Certificates of Analysis (COAs) to guarantee standard-setting laboratory results.

SKU: Tesamorelin & CJC-1295 Category: Peptide Blends Tags: Buy Peptides Online, Chondrocyte Kinetics, CJC-1295, GHRH Analog, Ipamorelin, Lab Supplies, Mod GRF 1-29, Peptide Blend, Pituitary Axis, Planex Supplies, Research Peptides, Secretagogue, Tesamorelin, USA Tested

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Advanced Triple-Pathway Pituitary Receptor Optimization Matrix

The Tesamorelin & CJC-1295 (Mod GRF 1-29) & Ipamorelin Peptide Blend from Planex Supplies represents a cutting-edge multi-peptide core engineered for advanced neuroendocrine research. By combining two structurally distinct Growth Hormone-Releasing Hormone (GHRH) receptor agonists with a highly selective ghrelin receptor agonist, this composite formulation allows investigators to study multi-channel signal integration, baseline versus pulsatile somatotroph kinetics, and temporal receptor crosstalk within the central nervous system without competitive pathway blockades.

Comprehensive Technical Specifications:

Tesamorelin (N-Terminus Modified Full-Length GHRH Analog)

Molecular Formula: C₂₂₁H₃₆₆N₇₂O₆₇S
Molecular Weight: 5136 g/mol
Sequence: trans-hexenoyl-acid-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-AsnSer-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-LeuGln-Asp-Ile-Met-Ser-Arg-GlnGln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu

CJC-1295 (Modified GRF 1-29 / Tetra-Substituted GHRH Fragment) (Note: Formulated without DAC for precise natural pulsatile simulation)

Molecular Formula: C₁₅₂H₂₅₂N₄₄O₄₂
Molecular Weight: 3367.954 g/mol
Sequence: YDADAIFTQSYRKVLAQLSARKL LQDILSR-NH2

Ipamorelin (Highly Selective Pentapeptide GHS)

Molecular Formula: C₃₈H₄₉N₉O₅
Molecular Weight: 711.868 g/mol
Sequence: Aib-His-D-2Nal-D-Phe-Lys

Key Areas of Scientific Research & Complementary Mechanisms:

Dual-GHRH Receptor Stability & Engineering: Tesamorelin and CJC-1295 (Mod GRF 1-29) act as the primary structural keys for pituitary GHRH receptors, but utilize separate biochemical modifications to bypass rapid clearance. Tesamorelin features a 44-amino-acid architecture stabilized with an N-terminal trans-3-hexenoic acid group (omega-amino acid modification) to resist metabolic clearance. In parallel, Mod GRF 1-29 uses a shortened 29-amino-acid segment featuring a modified D-Alanine at position two, Lysine at position eight, D-Phenylalanine at position fifteen, and N-methylglycine (Sarcosine) at position twenty-seven to prevent enzymatic degradation by DPP-4.
Adenylate Cyclase & cAMP-PKA Signaling Cascades: Upon receptor engagement, the dual GHRH agonists drive conformational shifts that activate membrane-bound adenylate cyclase, converting cellular adenosine triphosphate (ATP) into cyclic adenosine monophosphate (cAMP). Rising cAMP pools trigger protein kinase A (PKA) activation, which phosphorylates specialized intracellular targets. Preclinical models link this cascade to accelerated growth hormone synthesis and an observed 69% increase in total baseline hormone levels alongside a 55% rise in average natural pulse amplitude.
Phospholipase C Activation & Calcium Ion Influx: Operating independently via the ghrelin axis, Ipamorelin binds with high specificity to growth hormone secretagogue receptors (GHS-R1a) in the anterior pituitary gland and hypothalamus. This interaction triggers a phospholipase C (PLC) signaling pathway, cleaving lipids into secondary messengers IP3 and DAG. IP3 prompts calcium ion (Ca²⁺) mobilization from endoplasmic reticulum reserves, while DAG triggers protein kinase C (PKC) pathways. This independent surge in intracellular calcium forces the exocytosis of growth hormone-containing vesicles.
Downstream Anabolic Growth Factor Profiling: The combined secretagogue signaling drives a coordinated, system-wide increase in baseline growth factor outputs, primarily targeting hepatic synthesis of Insulin-Like Growth Factor-1 (IGF-1). Researchers utilize this exact multi-peptide matrix to study the systemic anabolic actions of IGF-1, its independent growth-stimulating traits on chondrocyte cartilage structures, and its regulation of protein turnover pathways without causing unwanted fluctuations in ACTH or cortisol markers.

The Planex Supplies Quality Standard

At Planex Supplies, we prioritize rigid quality control protocols to protect the accuracy and reproducibility of your laboratory findings. Our Tesamorelin + CJC-1295 + Ipamorelin matrix is synthesized to maximum purity and validated using high-performance liquid chromatography (HPLC). Every single batch is backed by a fully documented, third-party Certificate of Analysis (COA) issued by an independent laboratory in the USA.

Verified Purity: ≥ 99% purity guaranteed through mass spectrometry and HPLC profiling.
USA Vetted: Independently verified to ensure exact structural sequence identity, accurate molecular mass, and zero cross-contaminants.
Research Use Only: This compound is synthesized exclusively for in vitro laboratory experimentation and preclinical evaluation. Make sure to double-check the physical label to confirm this information.