Sermorelin & GHRP-6 & GHRP-2 Blend (9mg)

Buy Sermorelin & Ipamorelin Blend (10mg)

Name: Buy Sermorelin & Ipamorelin Blend (10mg) - Planex Supplies
SKU: Sermorelin & Ipamorelin Blend (10mg)
Price: 81.00 USD
Availability: InStock

$81.00

Buy the premium Sermorelin & Ipamorelin Peptide Blend from Planex Supplies. This advanced dual-action research formulation combines a core amino-terminal GHRH analog with a highly specific growth hormone secretagogue receptor (GHS-R1a) agonist. Together, they are engineered to evaluate parallel pituitary receptor convergence, intracellular cyclic AMP cascades, and skeletal muscle nitrogen retention. Every batch is independently USA-tested with transparent, documented Certificates of Analysis (COAs) to guarantee standard-setting laboratory integrity.

SKU: Sermorelin & Ipamorelin Blend (10mg) Category: Peptide Blends Tags: Buy Peptides Online, Endocrine Matrix, GHRH Analog, Ipamorelin, Lab Supplies, Nitrogen Homeostasis, Peptide Blend, Pituitary Axis, Planex Supplies, Research Peptides, Secretagogue, Sermorelin, USA Tested

Description
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Synergistic Dual-Pathway Pituitary Axis Research

The Sermorelin & Ipamorelin Peptide Blend from Planex Supplies pairs two distinct molecular structures studied for their concurrent, non-competing activity within the mammalian endocrine matrix. By activating separate receptor families—the Growth Hormone-Releasing Hormone (GHRH) pathway and the Ghrelin/Growth Hormone Secretagogue Receptor (GHS-R1a)—this blend provides an efficient preclinical platform for investigating multi-channel somatotroph stimulation, secondary messenger cross-talk, and downstream growth factor profiles.

Comprehensive Technical Specifications:

Sermorelin (Somatotropin-Releasing Factor Fragment)

Molecular Formula: C₁₄₉H₂₄₆N₄₄O₄₂S
Molecular Weight: 3357.9 g/mol
Sequence: Tyr-Ala-Asp-Ala-lle-Phe-DL-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH₂

Ipamorelin (Selective Ghrelin Receptor Agonist)

Molecular Formula: C₃₈H₄₉N₉O₅
Molecular Weight: 711.86 g/mol
Sequence: Aib-His-D-2-Nal-D-Phe-Lys-NH₂

Key Areas of Scientific Research & Complementary Mechanisms:

Sermorelin GHRH Adenylyl Cyclase Pathway: Sermorelin isolates the first 29 amino acids of endogenous GHRH, retaining complete biological receptor affinity despite its truncated structure. Upon binding to pituitary class B GPCRs, it upregulates the adenylyl cyclase signaling cascade, converting ATP into cyclic AMP (cAMP). High cAMP levels activate protein kinase A (PKA) to phosphorylate voltage-dependent calcium channels, provoking calcium ion influx into somatotroph cells and driving a 70% to 107% rise in 12-hour physiological peaks.
Ipamorelin Phospholipase C Target Activation: Operating independently of GHRH receptors, Ipamorelin acts as a highly selective pentapeptide mimic of ghrelin. It targets GHS-R1a receptors, initiating a conformational shift that triggers the phospholipase C (PLC) pathway. This breaks down intracellular matrices into secondary messengers IP3 and DAG. IP3 facilitates rapid calcium mobilization from the endoplasmic reticulum, while DAG activates protein kinase C (PKC), prompting vesicle exocytosis.
Targeted Pituitary Secretion Biomarkers: In vitro and in vivo models indicate that pairing these dual pathways induces massive, coordinated hormone secretion spikes. Ipamorelin research points to isolated, brief endocrine spikes up to 60-fold above baseline controls, elevating concentration peaks up to 26.6 ng/ml. Concurrently, Sermorelin exposure has been associated with a 100% expansion of nocturnal release and a 28% upregulation in systemic Insulin-Like Growth Factor 1 (IGF-1) markers, stabilizing the growth hormone axis.
Skeletal Muscle Anabolic & Homeostasis Modeling: Beyond neuroendocrine profiles, both peptides are heavily scrutinized for tissue protection and muscle contractile force preservation. Sermorelin is evaluated for its direct influence on lean mass distribution, dermal modifications, and skin thickness parameters. Concurrently, Ipamorelin is monitored for its ability to correct nitrogen wasting in hepatic structures under catabolic stress, showing a 20% reduction in liver urea-N production (CUNS) and downregulating catabolic enzyme mRNA.

The Planex Supplies Quality Standard

At Planex Supplies, we maintain strict analytical protocols to safeguard the precision and baseline reproducibility of your preclinical research. Our Sermorelin + Ipamorelin blend is synthesized to high structural specifications and verified via high-performance liquid chromatography (HPLC). Every single batch is independently vetted by independent laboratories in the United States and backed by accessible, documented Certificates of Analysis (COAs).

Verified Purity: ≥ 99% purity guaranteed through mass spectrometry and HPLC profiling.
USA Vetted: Rigorous independent batch evaluation ensures precise chemical identity, proper molecular weight, and complete freedom from cross-contaminants.
Research Use Only: This compound is synthesized exclusively for in vitro laboratory experimentation and preclinical evaluation. Make sure to double-check the physical label to confirm this information.